WASHINGTON — A massive spending bill to keep the federal government open through the end of September includes $300 million to continue cleaning the Great Lakes, $400 million for cleanup at a closed uranium enrichment plant in Piketon, and millions more for Ohio to combat opioid addiction.

The measure, likely to win congressional approval no later than Friday, provides $1.3 trillion for all federal agencies, boosting spending for both defense and domestic programs.

The bill sets aside $3 billion to reduce opioid addiction, of which $1 billion is earmarked for grants that will go directly to the states. Fifteen percent of the state grant money has been slated for states that have been the hardest by opioids, such as Ohio.

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