With GOP leaders’ current hopes of repealing Obamacare dangling by a thread after Sen. John McCain made his opposition public Friday, will lawmakers now turn to the course advocated by McCain, Ohio Sen. Sherrod Brown and Gov. John Kasich: forging a bipartisan compromise?

McCain’s decision likely dealt a death blow to the latest GOP Republican repeal attempt, a measure sponsored by two of his Republican colleagues: Lindsey Graham of South Carolina and Bill Cassidy of Louisiana. With only three GOP “no” votes enough to kill the bill, McCain joins Kentucky Sen. Rand Paul in outright opposition. A third Republican, Sen. Susan Collins of Maine, said Friday she is “leaning against the bill,” the Portland Press Herald reported.